Protein
Expression Services
Precision-driven recombinant production across Mammalian, Bacterial, and Yeast systems designed to overcome solubility and yield barriers.
Precision Host-System
Engineering
The journey from gene to functional protein requires precision and molecular expertise. Ponnaiya CAG offers end-to-end recombinant protein expression services designed to maximize biological activity and yield.
Our team specializes in overcoming common challenges such as codon bias, low solubility, and improper folding, ensuring you receive high-quality material for therapeutic or industrial use.
Codon Optimized
Sequence engineering for maximum translation rates.
Multiple Hosts
Bacterial, Yeast, and Mammalian systems.
Functional Yield
Focus on soluble and active protein fraction.
Native Folding
Expert PTM and folding validation.
Expression Platforms & Expertise
Mammalian Expression
Ideal for proteins requiring complex post-translational modifications (PTMs) and native human-like folding.
Bacterial (E. coli)
Most cost-effective and rapid system for high-yield production of recombinant proteins.
Yeast (Pichia pastoris)
Combines simple culture conditions with effective secretion and post-translational processing.
Codon Optimization
Specialized sequence engineering to overcome codon bias and maximize expression efficiency.
Expression Tuning
Optimizing vectors and promoters to find the 'sweet spot' for yield and biological activity.
Scale-Up Support
Transitioning from bench-scale optimization to small-batch production for downstream apps.
Optimized Expression Pipeline
Gene Synthesis
Codon-optimized DNA templates
Vector Design
Promoter & tag selection
Optimization
Testing host-vector compatibility
Cultivation
Aerobic/Anaerobic fermentation
Harvest & QC
Crude extract & yield assessment
Pichia pastoris ExcellenceTarget Strain
"Our specialists excel in the Pichia pastoris system, leveraging its rapid growth and effective secretion capacities to deliver complex, soluble active recombinant proteins."
Driving Protein Innovation
From bench-scale research to industrial application.
Therapeutic Antibodies
Industrial Enzymes
Diagnostic Antigens
Vaccine Development
Functional Studies
Drug Discovery
Expertise in
Yield & Solubility
"Our journey doesn't end at expression; we ensure that the protein produced is biologically active, properly folded, and ready for your most critical downstream applications."
Expression Packages
Customizable host-system solutions
Bacterial Express
E.coli Systems
Advanced PTM
Mammalian/Yeast Systems
Full Synthesis
Gene to Functional Protein
Pathway to
Pure Protein
Download our detailed protein expression catalogue to explore host system specs, expression timelines, and codon optimization workflows.